Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmacogenetics and pharmacokinetics of immunosuppressants: clinical correlations and disease activity control in Egyptian female patients with lupus nephritis.

Molecular biology reports - 16 May 2026

Elmowafy Ahmed Yahia, Elwasif Salwa, Shemies Rasha, Abdel-Rahman Ahmed Mansour, Zakaria Mahmoud M, Omar Sameha A, El-Gamal Randa, Ramadan Nehal M, Malek Hala Abdel

Abstract excerpt

PURPOSE: Mycophenolate mofetil (MMF) is widely used in lupus nephritis (LN), but interindividual variability in pharmacokinetics and pharmacogenetics may affect treatment response. This study investigated the relationship between MMF pharmacokinetics, key genetic polymorphisms, and therapeutic response in Egyptian female LN patients. METHODS AND RESULTS: In this prospective study, 53 female patients with active...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Egypt
Share to Glucuronosyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunosuppressive Agents

Share to Liver-Specific Organic Anion Transporter 1

Share to Lupus Nephritis

Share to Mycophenolic Acid

Share to Pharmacogenetics

Share to Treatment Outcome

Source

Identifiers

PMID: 42142189
DOI: 10.1007/s11033-026-11881-0

Genes

SLCO1B1
UGT2B7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmacogenetics and pharmacokinetics of immunosuppressants: clinical correlations and disease activity control in Egyptian female patients with lupus nephritis.PMID 42142189Read ↗

Pharmacogenetics and Pharmacokinetics of Immunosuppressants: Clinical Correlations and Disease Activity Control in Egyptian Female Patients with Lupus Nephritis.Semantic proximity Read ↗

Pharmacokinetics and pharmacogenomics of mycophenolic acid and its clinical correlations in maintenance immunosuppression for lupus nephritis.Semantic proximity Read ↗

Effects of uridine diphosphate glucuronosyltransferase 2B7 and 1A7 pharmacogenomics and patient clinical parameters on steady-state mycophenolic acid pharmacokinetics in glomerulonephritis.Semantic proximity Read ↗

Steroid-resistant nephrotic syndrome: pharmacogenetics and epigenetic points and views.Semantic proximity Read ↗

Influence of genetic polymorphisms on pharmacokinetics and treatment response of mycophenolic acid: a scoping reviewSemantic proximity Read ↗

The pharmacogenetics of mycophenolate mofetil in Tunisian renal transplant patients.Semantic proximity Read ↗

Influence of SLCO1B1 Polymorphisms on the Pharmacokinetics of Mycophenolic Acid in Renal Transplant Recipients.Semantic proximity Read ↗

Pharmacology and pharmacogenetics of prednisone and prednisolone in patients with nephrotic syndromeSemantic proximity Read ↗

Influence of Genetic Polymorphisms on Mycophenolic Acid Pharmacokinetics and Patient Outcomes in Renal Transplantation.Semantic proximity Read ↗

Trends in Precision Medicine and Pharmacogenetics as an Adjuvant in Establishing a Correct Immunosuppressive Therapy for Kidney Transplant: An Up-to-Date Historical OverviewSemantic proximity Read ↗

Study on the association of UGT1A9 gene c.98T>C polymorphism and mycophenolic acid plasma levels in renal transplant patients.Semantic proximity Read ↗

A pilot study of leukocyte expression patterns for drug metabolizing enzyme and transporter transcripts in autoimmune glomerulonephritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.