The germline landscape of pituitary adenomas: established and emerging predisposition genes.

Abstract excerpt

Pituitary adenomas are increasingly recognized to have a germline genetic component in a subset of patients, particularly those with young-onset disease, familial clustering or syndromic features. The spectrum of germline variants implicated in pituitary tumorigenesis has broadened considerably, with evidence of both established predisposition genes and a growing number of emerging candidate genes. Established...

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