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The landscape of germline variants in breast and colorectal cancer susceptibility genes in patients with pituitary tumours

25 Jun 2025

Abstract excerpt

PURPOSE: Heritable genetic contributions to familial and sporadic pituitary tumorigenesis are poorly understood. There is emerging evidence that germline variants in classical cancer susceptibility genes may increase the risk of pituitary tumour development. We aimed to identify and assess the rate of pathogenic germline variants in breast and colorectal cancer susceptibility genes that may promote pituitary...

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PMID: 40563065
DOI: 10.1007/s11060-025-05140-8

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