Article
Susceptibility to pituitary neoplasia related to MEN-1, CDKN1B and AIP mutations: an update.
Human molecular genetics - 15 Apr 2007
Karhu Auli, Aaltonen Lauri A
Abstract excerpt
Pituitary tumors are common intracranial neoplasms. Although histologically benign, pituitary tumors can cause significant morbidity due to their critical location, expanding size and oversecretion of pituitary hormone expression. The majority of pituitary tumors are sporadic, but some arise as a component of hereditary syndromes. Our understanding of these genetic conditions has expanded rapidly due to the...
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