Article
Prevalence, genetic variants and clinical implications of G-6-PD deficiency in Burkina Faso: a systematic review.
BMC medical genetics - 23 Nov 2017
Ouattara Abdoul Karim, Yameogo Pouiré, Traore Lassina, Diarra Birama, Assih Maléki, Compaore Tegwindé Rébéca, Obiri-Yeboah Dorcas, Soubeiga Serge Théophile, Djigma Florencia Wendkuuni, Simpore Jacques
Abstract excerpt
BACKGROUND: It is now well-known that some antimalarials such as primaquine may induce severe hemolytic anemia in people with G-6-PD deficiency. Antimalarial drug prescriptions must, therefore take into account the patient's G-6-PD status in malaria endemic areas such as Burkina Faso, where the prevalence of this genetic abnormality is relatively high. Although great clinical heterogeneity is observed depending...
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