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Article

Improved High-Throughput Raman-Activated Cell Sorting Yields a High-DHA Aurantiochytrium Mutant with Enhanced Lipid Recycling.

Journal of agricultural and food chemistry - 27 May 2026

Wang Sen, Wang Xixian, Sun Caili, Wan Weijian, Lan Chuanzeng, Song Xiaojin, Cui Qiu, Xu Jian, Ma Bo, Feng Yingang

Abstract excerpt

Industrial microbial strain breeding remains hindered by the inherent bottleneck of low-throughput phenotypic screening. Here, a high-throughput Raman-activated cell sorting strategy was employed to directly quantify the intracellular docosahexaenoic acid (DHA) content in single cells of the thraustochytrid Aurantiochytrium sp. SD116, eliminating the need for prolonged cultivation and lipid extraction. From a...

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PMID: 42133322
DOI: 10.1021/acs.jafc.6c02537

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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