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Article

APOE ε2/ε3 is associated with multi-layered protection against prostate cancer in Chinese men.

World journal of urology - 14 May 2026

Wang Kuan, Zhang Shizhen, Chen Mengli, Duan Xiuzhi, Xie Yiyi, Yang Xufeng, Zhong Yuhong, Yu Pan, Yang Meiying, Wei Zhenli, Tao Zhihua, Liu Weiwei

Abstract excerpt

PURPOSE: The association between apolipoprotein E (APOE) gene polymorphisms and prostate cancer (PCa) susceptibility exhibits population-specific variability, yet evidence in Chinese men remains limited. This study assessed the relationship between APOE variants and PCa risk, as well as their correlation with clinicopathological features in a Chinese cohort. METHODS: APOE polymorphisms (rs429358 and rs7412) were...

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Identifiers

PMID: 42133096
DOI: 10.1007/s00345-026-06459-1
PMCID: PMC13175999

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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