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Article

Integrative proteogenomic and observational analysis identifies potential biomarkers for latent autoimmune diabetes in adults.

Cardiovascular diabetology - 9 May 2026

Yang Yuanqin, Lu Jiawen, Wang Zhenqian, Lu Tianyuan, Ding Jin, Wang Ruofan, Zhou Sirui, Zhou Zhiguang, Hu Jingyi

Abstract excerpt

BACKGROUND: Latent autoimmune diabetes in adults (LADA) shares core genetic and immunological features with type 1 diabetes (T1D) but is frequently misdiagnosed as type 2 diabetes (T2D). With few biomarkers for its timely diagnosis and management, this study integrated proteome-wide Mendelian randomisation (MR) and observational clinical analysis to identify potential LADA biomarkers. METHODS: We performed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42106685
DOI: 10.1186/s12933-026-03203-2
PMCID: PMC13330287

Genes

CXCL10
SAA1
SAA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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