Article
Painful tonic spasms in neuromyelitis optica spectrum disorders: Prevalence, clinical phenotype, symptomatic management, and patient-reported burden in a Chinese cohort.
Multiple sclerosis and related disorders - 1 Jul 2026
Luo Wenjing, Du Yi, Wei Zhenshen, Huang Shuxin, Tang Jingqun, Tang Yulan, Wu Yuan
Abstract excerpt
BACKGROUND: Tonic spasms in neuromyelitis optica spectrum disorder (NMOSD) range from painless tonic posturing to painful tonic spasms (PTS). However, the real-world management, tolerability, and patient-reported burden of PTS remain insufficiently described. METHODS: We screened consecutive patients with NMOSD at a tertiary center in China between January 2020 and July 2025. PTS were identified through medical...
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