Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Primary Kaposiform hemangioendothelioma of the tibia: report of a case with a previously undescribed GNAQ mutation.

Skeletal radiology - 1 Sept 2026

Arcovito Giorgia, Gaeta Raffaele, Aringhieri Giacomo, Andreani Lorenzo, Lessi Francesca, Morelli Mariangela, Mazzanti Chiara Maria, Franchi Alessandro

Abstract excerpt

Primary occurrence of Kaposiform hemangioendothelioma (KHE) in bone is extremely rare. We report the radiologic, histopathologic and molecular features of a case of KHE affecting the tibia of an adult male, who presented with pain in the left knee initially associated with previous trauma. Radiographs showed an eccentric well-defined lytic lesion of the tibial epiphysis. On MRI, the lesion showed hypo to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Neoplasms
Share to Diagnosis, Differential

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to GTP-Binding Protein alpha Subunits, Gq-G11

Share to Magnetic Resonance Imaging

Share to Mutation

Share to Sarcoma, Kaposi

Share to Tomography, X-Ray Computed

Source

Identifiers

PMID: 42103999
DOI: 10.1007/s00256-026-05245-9

Genes

GNAQ
CD34

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Primary Kaposiform hemangioendothelioma of the tibia: report of a case with a previously undescribed GNAQ mutation.PMID 42103999Read ↗

Diffuse bone and soft tissue angiomatosis with GNAQ mutation.Semantic proximity Read ↗

Malignant transformation of fibrous dysplasia in long bones: a clinicopathological and molecular study of 19 cases.Semantic proximity Read ↗

Ousseos ephitelioid hemangioma with skip lesion identified by ZFP36 FOSB fusionSemantic proximity Read ↗

Epithelioid hemangioma of bone harboring FOS and FOSB gene rearrangements: A clinicopathologic and molecular study.Semantic proximity Read ↗

Chronic lymphedema in patients with kaposiform hemangioendothelioma: incidence, clinical features, risk factors and managementSemantic proximity Read ↗

Diagnostic Familiarity with Osteochondroma Among Primary Physicians: A Retrospective Analysis of 195 Referred CasesSemantic proximity Read ↗

Angiomatoid fibrous histiocytoma occurring at distal/acral extremity sites: clinicopathological and molecular study of 26 cases highlighting frequent myxoid histology and site-dependent genotypic variation.Semantic proximity Read ↗

Identification and characterization of NF1 and non-NF1 congenital pseudarthrosis of the tibia based on germline NF1 variants: genetic and clinical analysis of 75 patientsSemantic proximity Read ↗

A Novel Spindle Cell Population in a Case of Primary Osteoma Cutis With GNAS Mutation.Semantic proximity Read ↗

Gain-of-function mutation in PTPN11 in histiocytic sarcomas of Bernese Mountain Dogs.Semantic proximity Read ↗

Does This Imaging Make Me Look NFATC2 ? The Value of Radiologic-pathologic Correlation in NFATC2 -rearranged Sarcomas of Bone.Semantic proximity Read ↗

Diagnosis of Klippel-Trenaunay syndrome and extensive heterotopic ossification in a patient with a femoral fracture: a case report and literature review.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.