Article
Epithelioid hemangioma of bone harboring FOS and FOSB gene rearrangements: A clinicopathologic and molecular study.
Genes, chromosomes & cancer - 1 Jan 2021
Tsuda Yusuke, Suurmeijer Albert J H, Sung Yun-Shao, Zhang Lei, Healey John H, Antonescu Cristina R
Abstract excerpt
The diagnosis of epithelioid hemangioma (EH) remains challenging due to its rarity, worrisome histologic features, and locally aggressive clinical and radiographic presentation. Especially in the bone, EH can be misdiagnosed as a malignant vascular neoplasm due its lytic, often destructive or multifocal growth, as well as atypical morphology. The discovery of recurrent FOS and FOSB gene fusions in the...
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