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Article

Niche-specific metabolic phenotypes can be used to identify antimicrobial targets in pathogens.

PLoS biology - 1 Nov 2024

Glass Emma M, Dillard Lillian R, Kolling Glynis L, Warren Andrew S, Papin Jason A

Abstract excerpt

Bacterial pathogens pose a major risk to human health, leading to tens of millions of deaths annually and significant global economic losses. While bacterial infections are typically treated with antibiotic regimens, there has been a rapid emergence of antimicrobial resistant (AMR) bacterial strains due to antibiotic overuse. Because of this, treatment of infections with traditional antimicrobials has become...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39556591
DOI: 10.1371/journal.pbio.3002907
PMCID: PMC11611258

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