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Article

Beyond phenotype: The genomic heterogeneity of co-infecting Mycobacterium abscessus smooth and rough colony variants in cystic fibrosis patients.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 May 2021

Gutiérrez Ana Victoria, Baron Sophie Alexandra, Sardi Feyrouz Sonia, Saad Jamal, Coltey Bérengère, Reynaud-Gaubert Martine, Drancourt Michel

Abstract excerpt

Two unrelated cystic fibrosis patients were co-infected with Mycobacterium abscessus smooth and rough phenotypes. Smooth M. abscessus is proposed as the infecting form, and the subsequent loss of glycopeptidolipids in the host leads to a rough phenotype. Whole-genome sequencing (WGS) diagnosed two different M. abscessus strains in patient N°1 but only one strain in patient N°2. In patient N°1, rough isolate had...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33610476
DOI: 10.1016/j.jcf.2021.02.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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