Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Novel CFA3 Locus Encompassing KCNIP4 Is Associated with Idiopathic Epilepsy in Siberian Huskies.

Genes - 15 Apr 2026

Smith Tracy A, Potisk Leon

Abstract excerpt

Background/Objectives: Idiopathic epilepsy is a lifelong neurologic disorder in dogs, but its genetic basis remains incompletely understood in many breeds. This study aimed to identify risk-associated markers in Siberian Huskies, quantify their effects, assess potential risk modifiers, and characterize the shared haplotype background of the associated signal. Methods: A genome-wide association study was conducted...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dog Diseases
Share to Dogs
Share to Epilepsy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genome-Wide Association Study

Share to Haplotypes

Share to Polymorphism, Single Nucleotide

Source

Open in PubMed Open full text

Identifiers

PMID: 42074577
DOI: 10.3390/genes17040459
PMCID: PMC13115692

Genes

KCNIP4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Novel CFA3 Locus Encompassing KCNIP4 Is Associated with Idiopathic Epilepsy in Siberian Huskies.PMID 42074577Read ↗

Identification of a novel idiopathic epilepsy locus in Belgian Shepherd dogs.Semantic proximity Read ↗

Validation of a Chromosome 14 Risk Haplotype for Idiopathic Epilepsy in the Belgian Shepherd Dog Found to Be Associated with an Insertion in the RAPGEF5 Gene.Semantic proximity Read ↗

Identification of a common risk haplotype for canine idiopathic epilepsy in the ADAM23 gene.Semantic proximity Read ↗

A genome-wide association study for canine cryptorchidism in Siberian Huskies.Semantic proximity Read ↗

Complex disease and phenotype mapping in the domestic dog.Semantic proximity Read ↗

Parallel mapping and simultaneous sequencing reveals deletions in BCAN and FAM83H associated with discrete inherited disorders in a domestic dog breed.Semantic proximity Read ↗

Characterisation of canine KCNIP4: A novel gene for cerebellar ataxia identified by whole-genome sequencing two affected Norwegian Buhund dogs.Semantic proximity Read ↗

Differential Gene Expression Associated with Idiopathic Epilepsy in Belgian Shepherd Dogs.Semantic proximity Read ↗

Genomic analyses identify 15 susceptibility loci and reveal <i>HDAC2</i> , <i>SOX2-OT</i> , and <i>IGF2BP2</i> in a naturally-occurring canine model of gastric cancerSemantic proximity Read ↗

Risk loci for idiopathic epilepsy in Belgian Shepherd dogs.Semantic proximity Read ↗

A novel locus on canine chromosome 13 is associated with cataract in the Australian Shepherd breed of domestic dog.Semantic proximity Read ↗

Somatic Mutation of PIK3CA (H1047R) Is a Common Driver Mutation Hotspot in Canine Mammary Tumors as Well as Human Breast CancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.