Article
The rs2442598 polymorphism in the ANGPT-2 gene is associated with risk for diabetic retinopathy in patients with type 1 diabetes mellitus in a Brazilian population.
Archives of endocrinology and metabolism - 24 Nov 2021
Dieter Cristine, Lemos Natália Emerim, de Faria Corrêa Nathalia Rodrigues, Costa Aline Rodrigues, Canani Luís Henrique, Crispim Daisy, Bauer Andrea Carla
Abstract excerpt
OBJECTIVE: As studies have reported the involvement of angiopoietin-2 (ANGPT-2) in the pathogenesis of diabetic retinopathy (DR), the aim of this study was to investigate the association between the ANGPT-2 rs2442598 polymorphism and DR. METHODS: This case-control study comprised 107 patients with type 1 diabetes mellitus (T1DM) and DR (cases) and 129 patients with T1DM without DR (controls) and with ≥ 10 years...
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