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Article

Genetic Risk Factors and Clinical Implications of Glaucoma in the Saudi Population: A Review.

International journal of molecular sciences - 14 Apr 2026

Alotaibi Abdullah Faisal, Maawadh Lojain Mohammed A, Almutairi Mohammed Naji Obaid, Hameed Syed, Malik Rizwan, Abu-Amero Khaled K

Abstract excerpt

Most glaucoma genetic data derive from European and East Asian cohorts, leaving high-consanguinity Middle Eastern populations under-characterized. This review synthesizes 33 Saudi-specific genetic studies (2014-2024, >9000 participants) to define a population-level glaucoma genetic architecture that diverges substantially from global models and carries direct precision medicine implications. Three findings...

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Share to Cytochrome P-450 CYP1B1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Latent TGF-beta Binding Proteins

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Source

Open in PubMed Open full text

Identifiers

PMID: 42074148
DOI: 10.3390/ijms27083506
PMCID: PMC13116526

Genes

CYP1B1
ACVR1
APOE
LTBP2
MTHFR
MYOC
NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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