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Article

CD135 (FLT3 receptor) expression as an indicator of prognosis in patients with de novo acute myeloid leukemia.

Annals of hematology - 2 May 2026

Nie Jinhong, Gao Lu, Shao Yingchun, Yang Li, Cao Junjie, Xu Jinge, Wang Yuhang, Zhang Yuqi, Cui Tong, Zhou Shiyuan, Zhu Wenjuan, Zhu Mingqing, Ma Xiao, Wu Depei, Wu Xiaojin

Abstract excerpt

Acute myeloid leukemia (AML) blasts often have high CD135 (FLT3 receptor) expression, but its clinical impact is unclear. We analyzed CD135 expression, and the clinical characteristics and outcomes of 214 patients with de novo AML diagnosed between October 2022 and May 2024. Subsequently, we collected data on additional 78 patients, diagnosed with AML at four medical centers from June to December 2024, for...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 42067641
DOI: 10.1007/s00277-026-07010-3
PMCID: PMC13134979

Genes

FLT3
CD33
CD34
DNMT3A
NPM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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