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Article

Increased coexpression of c-KIT and FLT3 receptors on myeloblasts: independent predictor of poor outcome in pediatric acute myeloid leukemia.

Cytometry. Part B, Clinical cytometry - 1 Jan 2000

Sharawat Surender Kumar, Gupta Ritu, Raina Vinod, Kumar Lalit, Sharma Atul, Iqbal Sobuhi, Bakhshi Radhika, Vishnubhatla Sreenivas, Bakhshi Sameer

Abstract excerpt

BACKGROUND: Significance of mutations in FLT3 and c-KIT genes in AML has been well established, but role of their coexpression has not been evaluated. The aim of this study was to evaluate clinical significance of FLT3 (CD135) and c-KIT (CD117) coexpression on myeloblasts in AML. METHODS: Using f...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

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Share to Proto-Oncogene Proteins c-kit

Source

Identifiers

PMID: 23740774
DOI: 10.1002/cyto.b.21098

Genes

FLT3
EFS
KIT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23740774-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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