Article
Impact of FLT3 Receptor (CD135) Detection by Flow Cytometry on Clinical Outcome of Adult Acute Myeloid Leukemia Patients.
Clinical lymphoma, myeloma & leukemia - 1 Aug 2018
Kandeel Eman Z, El Sayed Ghada, Elsharkawy Nahla, Eldin Dalia Negm, Nassar Hanan R, Ibrahiem Dalia, Amin Randa, Hanafi Marwa, Khalil Mohamed, Kamel Azza
Abstract excerpt
BACKGROUND: The significance of FMS-like tyrosine kinase 3 (FLT3)-ITD mutation in acute myeloid leukemia (AML) prognosis has been well established. The aims of this study were to investigate the prognostic impact of the FLT3 protein (CD135) expression and its association with FLT3-ITD mutation, and to identify its role in minimal residual disease. PATIENTS AND METHODS: CD135 was measured by flow cytometry on...
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