Article
Association analysis of PTPN1 gene SNP with retinopathy and nephropathy in type 2 diabetes mellitus and development of predictive line graph in Chinese population.
Scientific reports - 1 May 2026
Dong Qian, Xu Huan, Xu Pengjie, Shen Danqing, Liu Jiang
Abstract excerpt
Our research endeavored to formulate a patient-specific prognostic algorithm and elucidate the interconnection between critical genetic polymorphisms at PTPN1 loci and the predisposition to small vessel pathologies in Han Chinese subjects presenting with T2DM. From January 1, 2019, to June 30, 2024, a total of 3,847 patients with T2DM were enrolled in this cross-sectional case-control study. They were grouped...
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