Article
Single nucleotide polymorphisms of vascular endothelial growth factor gene intron 2 are markers for early progression of diabetic retinopathy in Japanese with type 1 diabetes.
Clinica chimica acta; international journal of clinical chemistry - 1 Apr 2009
Nakanishi Koji, Watanabe Chizuru
Abstract excerpt
BACKGROUND: Few studies investigated the relationship between single nucleotide polymorphisms (SNPs) of vascular endothelial growth factor (VEGF) gene and time to the development and progression of diabetic retinopathy. METHODS: Eight SNPs of VEGF gene were typed using TaqMan assays in 175 Japanese patients with type 1 diabetes. Fundi were evaluated longitudinally. The overall mean HbA1c value was calculated to...
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