Regulation of the Cell Wall Integrity pathway at the contact site between mating partners in yeast.

Abstract excerpt

The fungal cell wall is constantly remodeled to allow cell growth, but any holes in the cell wall would lead to catastrophic lysis. The "Cell Wall Integrity" pathway (CWI) detects cell wall defects and promotes cell wall thickening or repair to protect cell integrity. However, cell walls must be removed at contact sites between fusing cells during mating or mycelium formation. Here, we show that in Saccharomyces...

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