Article
Evaluation of the incremental prognostic value of the combination of CYP2C19 poor metabolizer status and ABCB1 3435 TT polymorphism over conventional risk factors for cardiovascular events after drug-eluting stent implantation in East Asians.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Aug 2016
Park Mahn-Won, Her Sung Ho, Kim Chan Joon, SunCho Jung, Park Gyung-Min, Kim Tae-Seok, Choi Yun-Seok, Park Chul-Soo, Koh Yoon-Seok, Park Hun-Jun, Kim Pum-Joon, Chung Wook-Sung, Seung Ki-Bae, Kim Ho-Sook, Shin Jae-Gook, Chang Kiyuk
Abstract excerpt
PURPOSE: We evaluated the incremental prognostic value of combining the CYP2C19 poor metabolizer (PM) and ABCB1 3435 TT for adverse clinical outcomes over conventional risk factors in a percutaneous coronary intervention (PCI) cohort. METHODS: We enrolled 2,188 patients. The primary end point was a composite of death from any cause, nonfatal myocardial infarction (MI), and stroke during 1-year follow-up. The...
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