Article
Conserved rod-to-spherical shape transitions in Escherichia coli through primordial experimental adaptations.
Bioscience reports - 20 May 2026
Lu Hui, Zhang Yueyue, Xu Boying, Tian Di, Xia Yang, Yomo Tetsuya, Xu Jian
Abstract excerpt
Cell shape plays a fundamental role in bacterial physiology, yet the evolutionary stability of morphological adaptations remains poorly understood. Our previous work suggested that Escherichia coli can evolve a spherical form under primordial-like conditions. Here, we extended experimental evolution for approximately 1000 generations in oleic acid vesicle (OAV)-supplemented media mimicking primordial...
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