Article
Revealing Cell Envelope Heterogeneity in Two Stable Escherichia coli L-Forms.
International journal of molecular sciences - 30 Mar 2026
Xu Boying, Zhang Yueyue, Liu Yunfei, Hoischen Christian, Westermann Martin, Kashiwagi Akiko, Kato Tatsuya, Yomo Tetsuya, Xu Jian
Abstract excerpt
Long-term adapted cell wall-deficient (L-forms) bacteria show unique cell shapes and growth patterns compared to wild-type bacteria. However, quantitative analysis to assess the morphological heterogeneity of existing L-forms is limited. In this study, we validated that two stable L-form strains of Escherichia coli (NC-7 and LWF+) hold spherical or pleomorphic morphology in confocal and electron microscopy. Using...
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