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Article

Biomechanical Phenotyping of Forced Expiration for Precision Pulmonary Rehabilitation: A Machine Learning Approach to Identify Structural and Kinetic Drivers.

Advances in respiratory medicine - 17 Apr 2026

Sangkarit Noppharath, Tapanya Weerasak

Abstract excerpt

BACKGROUND: Standard spirometry fundamentally overlooks the mechanical dynamics of forced expiration. This study derived novel biomechanical parameters to establish functional phenotypes and predict clinical respiratory impairments. METHODS: Utilizing 16,596 acceptable spirometry records from NHANES (2007 to 2012), parameters reflecting kinetic power, mass constraint, and airway instability were mathematically...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 42041274
DOI: 10.3390/arm94020026
PMCID: PMC13114150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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