Blood-based biomarkers of ferroptosis in Parkinson's disease.

doi:10.1016/j.nbd.2026.107414

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Blood-based biomarkers of ferroptosis in Parkinson's disease.

Neurobiology of disease - 15 Jun 2026

Huin Vincent, Cailliau Emeline, Poupelin Clément, Garçon Guillaume, Dutheil Mary, Simonin Ophélie, Beauval Nicolas, Labreuche Julien, Blum David, Moreau Caroline, Hainque Elodie, Marques Ana, Eusebio Alexandre, Benatru Isabelle, Brefel-Courbon Christine, Maltete David, Giordana Caroline, Tir Melissa, Thobois Stéphane, Brandel Jean-Philippe, Jarraya Béchir, Hopes Lucie, Rascol Olivier, Corvol Jean-Christophe, Devos David, Rolland Anne-Sophie

Abstract excerpt

BACKGROUND: As Parkinson's disease progresses, patients require second-line treatments such as subthalamic stimulation, the benefits of which may be diminished by the onset of non-dopaminergic axial motor and cognitive disorders. This study aimed to identify blood biomarkers of ferroptosis for predicting the progression of Parkinson's disease at the stage of L-DOPA-related complications. METHODS: We analyzed 598...

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PMID: 42035924
DOI: 10.1016/j.nbd.2026.107414

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