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Distinct respiratory and neurological disease phenotypes in lethal Nipah virus Malaysia versus Bangladesh infection in IFNAR knockout mice.

Antiviral research - 1 Jun 2026

Sorvillo Teresa E, Davies Katherine A, Welch Stephen R, Coleman-McCray JoAnn D, Harmon Jessica R, Aida-Ficken Virginia, Montgomery Joel M, Lo Michael K, Spiropoulou Christina F, Spengler Jessica R

Abstract excerpt

Nipah virus (NiV) strains Malaysia (NiV-M) and Bangladesh (NiV-B) cause severe respiratory and neurological disease in humans, yet no FDA-approved medical countermeasures currently exist. Since 2000, NiV-B has been responsible for most human outbreaks, underscoring the need for relevant animal models of this strain to support public health preparedness. While mice offer a scalable platform for high-throughput in...

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PMID: 42035922
DOI: 10.1016/j.antiviral.2026.106420

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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