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Lethal Viral Sepsis/Septic Shock in Getah Virus Infected <em style="mso-bidi-font-style: normal;">Ifnar1-/-</em> Mice

2026-08-27

Abstract excerpt

Getah virus (GETV) is a mosquito borne Old World alphavirus that has recently increased its geographic range, particularly in China. GETV causes rheumatic disease in horses, but in recent years its primary impact has been lethal infections in newborn piglets. Herein we characterize a lethal Ifnar1-/- mouse model of GETV, which recapitulated many of the features seen in piglets. These include lethality, high viremi...

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Literature Corpus work
f83aebfa-7193-5474-8b31-55b050758593
DOI
10.20944/preprints202608.2029.v1
Open publication

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Lethal Viral Sepsis/Septic Shock in Getah Virus Infected <em style="mso-bidi-font-style: normal;">Ifnar1-/-</em> MiceDOI 10.20944/preprints202608.2029.v1
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