CrohnTwin-X: An explainable digital twin framework for predicting postoperative recurrence in Crohn's disease using multi-omics and clinical features.

Abstract excerpt

BACKGROUND: Crohn's disease (CD) is a chronic inflammatory disorder with a high rate of postoperative recurrence, posing major challenges for long-term management. Conventional clinical indices have limited capacity for individualized prognostic prediction. While Digital Twin (DT) technology-virtual replicas of individual patients-offers a transformative paradigm for clinical decision support, its application in...

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