Article
Hendra virus genotypes 1 and 2 differ in V protein-mediated immune evasion.
The Journal of general virology - 1 Apr 2026
Tripp Melanie N, Rawlinson Stephen M, Edwards Sarah J, David Cassandra T, Marsh Glenn A, Halpin Kim, Moseley Gregory W
Abstract excerpt
Hendra virus (HeV) is a highly pathogenic virus endemic to Australia that causes lethal infections in horses and humans following spillover from bat reservoirs. There are two known genotypes: genotype 1 and 2 (HeV-g1 and HeV-g2). Both have caused lethal disease in horses, but HeV-g1 causes a more severe disease than HeV-g2 in non-human primates. The molecular mechanisms underlying these differences are poorly...
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