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Article

Evaluation of immune responses following infection of ponies with an EHV-1 ORF1/2 deletion mutant

7 Feb 2011

Abstract excerpt

Equine herpesvirus-1 (EHV-1) infection remains a significant problem despite the widespread use of vaccines. The inability to generate a protective immune response to EHV-1 vaccination or infection is thought to be due to immunomodulatory properties of the virus, and the ORF1 and ORF2 gene products have been hypothesized as potential candidates with immunoregulatory properties. A pony infection study was...

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PMID: 21314906
DOI: 10.1186/1297-9716-42-23

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