Article
Robotic Duodenal Sleeve Resection for Gastrointestinal Stromal Tumor with Rare Exon 8 KIT Mutation Following Neoadjuvant Imatinib.
Journal of visualized experiments : JoVE - 3 Apr 2026
Niemann Britney, Puleo Amanda, Sestito Michael P, Schmidt Carl R, Boone Brian A
Abstract excerpt
Gastrointestinal stromal tumors (GISTs) predominantly arise in gastric tissue, with only 5% occurring in the duodenum. While surgery remains the cornerstone of treatment, patients with large tumors or a high risk of recurrence may benefit from targeted therapy. Most GISTs harbor mutations in the KIT receptor tyrosine kinase, making them potentially responsive to tyrosine kinase inhibitors (TKIs) such as imatinib....
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