Article
GABRB3 Gene Polymorphisms Influences the Analgesic Response to Acupuncture Treatment in Patients With Chronic Knee Pain: A Randomized Controlled Neuroimaging Transcriptomics Study.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 30 Apr 2026
Wu Sai, Wu Wanxia, Zhou Jun, Cheng Shirui, Dong Xiaohui, Chen Yang, Tang Chenjian, He Wenhua, Zeng Fang, Liang Fanrong, Li Zhengjie
Abstract excerpt
The mechanisms underlying individual variability in acupuncture analgesia among patients with chronic pain remain unclear. This randomized controlled trial investigated the core mechanisms of differential responses to acupuncture from genetic, neuroimaging, and transcriptomic perspectives in patients with chronic pain due to knee osteoarthritis (KOA). A total of 180 KOA chronic knee pain patients were randomly...
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