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Article

Neonatal platelets differentiate monocytes to a myeloid-derived suppressor cell phenotype.

Blood - 30 Jul 2026

Maurya Preeti, O'Reilly Daniel, Hilt Zachary T, Livada Alison C, McGrath Kathleen E, Li Chen, Ture Sara K, Malloy Michael W, Tun Ei Thanda, Palis James, Morrell Craig N

Abstract excerpt

ABSTRACT: Adult platelets are relatively enriched in immune-related molecules compared with neonatal platelets, but neonatal platelets express some growth factors and enzymes at comparatively higher levels. This makes a prediction of platelet-immune cell interaction outcomes in neonates a challenge, as they are likely dependent on the cell type and tissue environment at the time of injury or infection. Our...

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Identifiers

PMID: 41980018
DOI: 10.1182/blood.2025028734
PMCID: PMC13487479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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