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Article

Granulocytic myeloid-derived suppressor cells from human cord blood modulate T-helper cell response towards an anti-inflammatory phenotype.

Immunology - 1 Sept 2017

Köstlin Natascha, Vogelmann Margit, Spring Bärbel, Schwarz Julian, Feucht Judith, Härtel Christoph, Orlikowsky Thorsten W, Poets Christian F, Gille Christian

Abstract excerpt

Infections are a leading cause of perinatal morbidity and mortality. The outstandingly high susceptibility to infections early in life is mainly attributable to the compromised state of the neonatal immune system. One important difference to the adult immune system is a bias towards T helper type 2 (Th2) responses in newborns. However, mechanisms regulating neonatal T-cell responses are incompletely understood....

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Identifiers

PMID: 28464218
DOI: 10.1111/imm.12751
PMCID: PMC5543463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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