Article
Deep learning framework for quantifying self-organization in Myxococcus xanthus.
Proceedings of the National Academy of Sciences of the United States of America - 21 Apr 2026
Zhang Jiangguo, Caro Eduardo A, Chen Peiying, Khan Trosporsha Tasnim, Murphy Patrick A, Shimkets Lawrence J, Patel Ankit B, Welch Roy D, Igoshin Oleg A
Abstract excerpt
Under starvation, Myxococcus xanthus bacteria initiate a multicellular developmental program in which cells move to form fruiting bodies and differentiate into distinct cell types. Many genes affecting this process have been identified, and it is assumed that perturbing genes within the same pathway induces similar changes in the phenotype, although these changes may be subtle or obscured by pleiotropy. However,...
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