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Article

Developmental validation of a novel all-in one assay of X chromosomal multi-insertion/deletion loci for forensic genetics.

Scientific reports - 28 Dec 2024

Zhang Hongling, Huang Xiaolan, Zheng Yangyang, Zhu ShengJie, Zhong Min, Gu Changyun, Tian Shunyi, Chen Li, Ran Qianchong, Ren Zheng, Wang Qiyan, Yang Meiqing, Ji Jingyan, Deng Shiying, Huang Jiang, Jin Xiaoye

Abstract excerpt

Multi-insertion/deletion polymorphisms (Multi-InDels), as the novel genetic markers, show great potential in forensic research. Whereas, forensic researchers mainly focus on the multi-InDels on the autosomes, which can provide relatively limited information in some complex paternity cases. In this study, a novel X chromosomal multi-InDel multiplex amplification system was designed, containing 22 multi-InDels and...

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Chromosomes, Human, X
Forensic Genetics
Genetic Loci
INDEL Mutation
Microsatellite Repeats

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Multiplex Polymerase Chain Reaction

Polymorphism, Genetic

Reproducibility of Results

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Identifiers

PMID: 39733001
DOI: 10.1038/s41598-024-82609-y
PMCID: PMC11682147

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