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Genetic interactions between bioactive ingredients in traditional Chinese medicine and major depressive disorder, bipolar disorder, and schizophrenia.

Computational biology and chemistry - 1 Aug 2026

Xu Yusen, Deng Bin, Li Qinying, Li Linjie, Du Yujing, Qin Yanjie, Hu Junrui, Zhai Xuejia, Lu Yongning

Abstract excerpt

AIM: This study explored the genetic interactions between Traditional Chinese Medicine (TCM) bioactive ingredients and major psychiatric disorders, namely major depressive disorder (MDD), bipolar disorder (BIP), and schizophrenia (SCZ). METHOD: Predicting TCM targets using network pharmacology. Genome-wide association study (GWAS) summary statistics were analyzed using Multi-marker Analysis of Genomic Annotation...

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PMID: 41965146
DOI: 10.1016/j.compbiolchem.2026.109045

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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