Article
Blood neutrophil genetics highlight the role of neutrophils in early childhood asthma and viral respiratory illnesses.
The Journal of allergy and clinical immunology - 1 Jul 2026
Luo Yang, Eliasen Anders Ulrik, Fischer-Rasmussen Kasper, Thorsen Jonathan, Brustad Nicklas, Jensen Signe Kjeldgaard, Chen Liang, Sultan Tamo, Thysen Anna Hammerich, Linneberg Allan, Werge Thomas, Bybjerg-Grauholm Jonas, Bækvad-Hansen Marie, Brix Susanne, Stokholm Jakob, Chawes Bo, Pedersen Casper-Emil Tingskov, Bønnelykke Klaus
Abstract excerpt
BACKGROUND: Neutrophils are key in eliminating bacterial and fungal pathogens, but they are less effective against viruses. Excessive neutrophil activity may indicate dysregulated immunity preceding childhood asthma and viral respiratory illnesses. OBJECTIVE: We investigated if genetic predisposition to an excessive neutrophil activation is linked to childhood asthma and viral respiratory illnesses. METHODS:...
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