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Article

Mapping of DOG1 expression in colorectal carcinomas.

Pathology - 1 Jun 2026

Baron Julie, Lagrue Eric, Normand Adeline, Denis Marc G, Duchalais Emilie, Mosnier Jean-François

Abstract excerpt

Discovery on Gastrointestinal stromal tumour (DOG1) could deliver mitogen/survival signalling in colorectal carcinoma (CRC) cell lines. DOG1 is a major calcium-activated chloride channel expressed in mesenchymal and epithelial cells where it governs secretion of fluid and mucus. This study details DOG1 expression in various histopathological subtypes of CRC and assesses the relationship between DOG1 expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41946635
DOI: 10.1016/j.pathol.2025.12.003

Genes

BRAF
CDX2
KRAS
MLH1
MSH2
MSH6
MUC2
MUC5AC
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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