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Article

Interaction between fluoride exposure and bone metabolism-related gene polymorphisms in the susceptibility to essential hypertension.

Ecotoxicology and environmental safety - 1 Feb 2026

Gao Yue, Wang Qingbo, Yang Shuaifei, Wu Junhua, Qin Ming, Wang Xin, Liu Xiaona, Jiang Yuting, Ogutu James, Gao Yanhui, Yang Yanmei

Abstract excerpt

BACKGROUND: Groundwater contaminated with high fluoride levels poses a global public health concern. While fluoride exposure has been linked to hypertension, the role of genetic polymorphisms in bone metabolism-related genes in modulating this relationship remains unclear. OBJECTIVE: This study aimed to investigate the associations between fluoride exposure, polymorphisms in bone metabolism-related genes, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 41707530
DOI: 10.1016/j.ecoenv.2026.119903

Genes

ANP32A
LRP5
SMAD3
COL11A1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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