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Article

Associations of MTHFR and MTRR polymorphisms with serum lipid levels in Chinese hypertensive patients.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 May 2014

Jiang Shanqun, Zhao Ruimeng, Pan Mingluo, Venners Scott A, Zhong Guisheng, Hsu Yi-Hsiang

Abstract excerpt

OBJECTIVE: To examine the effects of the methylenetetrahydrofolate reductase (MTHFR) and methionine synthase reductase (MTRR) gene polymorphisms and their interactions with environmental factors on serum lipid levels. METHODS: We investigated totally 340 patients with essential hypertension, from Dongzhi community, Anhui, China. High-throughput TaqMan allelic discrimination assay was used for the genotyping of...

Topics

Adult
China
Female
Ferredoxin-NADP Reductase
Genotype
Homocysteine
Humans
Hypertension
Lipids
Male
Methylenetetrahydrofolate Reductase (NADPH2)

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 23188888
DOI: 10.1177/1076029612467226

Genes

MTRR
MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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