Silent evolution: β-lactam resistance acquisition in a virulent Salmonella enterica paratyphi B during systemic therapy despite clinical cure; A case report.

Abstract excerpt

The emergence of antimicrobial resistance during therapy is often monitored solely at the site of clinically apparent infection, potentially overlooking cryptic evolution in unexamined anatomical reservoirs. We report a case of acute cholecystitis caused by a virulent Salmonella enterica serovar Paratyphi B. While the bile isolate was susceptible to β-lactams, a fecal isolate obtained on day 7 of otherwise...

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