Article
Frequency, genetic mechanisms and factors associated with fluoroquinolone (pre-XDR) and aminoglycoside resistance among multidrug-resistant tuberculosis cases in Northwestern Nigeria.
BMC infectious diseases - 28 Mar 2026
Mamuda Kasimu, Aliyu Muhammad Sani, Suleman Mikailu, Ibrahim Abba Kasim, Song Abubakar Mohammed, Garba Bala Yazeed, Aminu Dalhatu Abdullahi, Dan-Inna Muhammad Zaharadeen, Mathew Gaius, Salihu Hamisu Mohammed, Hussaini Ibrahim Muhammed, Abdullahi Idris Nasir
Abstract excerpt
BACKGROUND: Rifampicin-resistant Mycobacterium tuberculosis (MTB), a critical priority pathogen, becomes highly complicated when it develops into pre-extensively drug-resistant (pre-XDR) and is an exceptional challenge for global TB control efforts. This study aims to determine the frequency and mutations associated with fluoroquinolone (FLQ) and aminoglycoside (AMG) resistance in MTB isolates from patients with...
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