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Separating sperm from cell mixtures by using a bubble-based acoustofluidic filtration device for forensic DNA analysis.

Forensic science international. Genetics - 1 Jun 2026

Hwa Hsiao-Lin, Wan Ting-Yu, Su Chih-Wen, Lee Tsui-Ting, Tzeng Li-Yu, Lu Yen-Wen, Lee James Chun-I

Abstract excerpt

Forensic DNA analysis of a victim's oral or vaginal swab containing an offender's sperm is crucial in sexual assault investigations. This study evaluated the effectiveness of a bubble-based acoustofluidic filtration (BAF) device for separating sperm from mixtures of sperm and buccal or vaginal epithelial cells to enhance downstream male DNA contributor analysis. Sperm were separated from 32 two-person (1 man and...

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PMID: 41880769
DOI: 10.1016/j.fsigen.2026.103494

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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