Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Perceived partner substance use, genetic predispositions, and their associations with problematic alcohol use, emotional well-being, and relationship quality.

Psychological medicine - 24 Mar 2026

Cooke Megan E, Kuo Sally I-Chun, Lumpe Erin, Aliev Fazil, Brislin Sarah J, Bucholz Kathleen K, Chan Grace, Dick Danielle M, Edenberg Howard J, Kamarajan Chella, Kramer John, Kuang Weipeng, Kuperman Samuel, McCutcheon Vivia V, Neale Zoe, Plawecki Martin H, Porjesz Bernice, Rabinowitz Jill A, Salvatore Jessica E

Abstract excerpt

BACKGROUND: Romantic relationships are important contexts for substance use and emotional well-being. We tested the hypotheses that (i) genetic predispositions for alcohol consumption would be positively associated with partner substance use, (ii) partner substance use would moderate genetic influences on one's own alcohol outcomes, and (iii) partner discordance in substance use would be associated with lower...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Drinking

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alcoholism

Share to Genetic Predisposition to Disease

Share to Genetic Risk Score

Share to Interpersonal Relations

Share to Sexual Partners

Share to Substance-Related Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 41873527
DOI: 10.1017/S0033291726103237
PMCID: PMC13040299

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Perceived partner substance use, genetic predispositions, and their associations with problematic alcohol use, emotional well-being, and relationship quality.PMID 41873527Read ↗

Polygenic Risk for Alcohol Misuse is Moderated by Romantic Partnerships: Primarily in MenSemantic proximity Read ↗

The genetic architecture of substance use and its diverse correlations with mental health traits.Semantic proximity Read ↗

Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits.Semantic proximity Read ↗

Sex-Specific Genetic Architecture and Comorbidities of Alcohol Use BehaviorsSemantic proximity Read ↗

Peer substance involvement modifies genetic influences on regular substance involvement in young women.Semantic proximity Read ↗

The Influence of Spousal Genotype on Alcohol Problems in Marriage.Semantic proximity Read ↗

Multi-ancestry study of the genetics of problematic alcohol use in over 1 million individuals.Semantic proximity Read ↗

Associations between polygenic risk of substance use and use disorder and alcohol, cannabis, and nicotine use in adolescence and young adulthood in a longitudinal twin studySemantic proximity Read ↗

The Influence of Spousal Genotype on Alcohol Problems in MarriageSemantic proximity Read ↗

Genetic nurture in intergenerational transmission of substance use.Semantic proximity Read ↗

Incorporating Functional Genomic Information to Enhance Polygenic Signal and Identify Variants Involved in Gene-by-Environment Interaction for Young Adult Alcohol Problems.Semantic proximity Read ↗

Three mutually informative ways to understand the genetic relationships among behavioral disinhibition, alcohol use, drug use, nicotine use/dependence, and their co-occurrence: twin biometry, GCTA, and genome-wide scoring.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.