Article
Unveiling the prognostic and therapeutic landscape of the zinc transporter protein SLC39A family in colorectal cancer through multi-omics and machine learning approaches.
Clinical and experimental medicine - 21 Mar 2026
Chen Haizhen, Chen Chaozhao, Chen Jie, Zheng Huang, Zhu Xinhao, Yu Qianru, Zhou Jiajie, Zong Jiasheng, Lu Tingyan, Sun Jing, Shao Yanfei, Zheng Minhua
Abstract excerpt
Colorectal cancer (CRC) remains a significant global health challenge due to its high prevalence and mortality rates. Zinc transporter proteins of the SLC39A family are crucial mediators of metal ion transport and have been implicated in numerous diseases, including cancer. However, the specific molecular mechanisms underpinning their impact on CRC progression remain poorly understood. By analyzing thousands of...
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