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Article

Comprehensive analyses of solute carrier family members identify SLC12A2 as a novel therapy target for colorectal cancer.

Scientific reports - 23 Feb 2024

Chen Dan-Yang, Zhang Yang-Yang, Nie Hai-Hang, Wang Hai-Zhou, Qiu Pei-Shan, Wang Fan, Peng Ya-Nan, Xu Fei, Zhao Qiu, Zhang Meng

Abstract excerpt

As the largest transporter family impacting on tumor genesis and development, the prognostic value of solute carrier (SLC) members has not been elucidated in colorectal cancer (CRC). We aimed to identify a prognostic signature from the SLC members and comprehensively analyze their roles in CRC. Firstly, we downloaded transcriptome data and clinical information of CRC samples from GEO (GSE39582) and TCGA as...

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Identifiers

PMID: 38396064
DOI: 10.1038/s41598-024-55048-y
PMCID: PMC10891168

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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