Article
A pangenome reference and population studies link structural variants with breeding traits in Gossypium hirsutum.
Nature genetics - 1 Apr 2026
Zhang Yan, Sun Zhengwen, Tian Shilin, Wu Liqiang, Gu Qishen, Ke Huifeng, Zhang Guiyin, Chen Bin, Wang Zhicheng, Zhang Jin, Zhang Xinyu, Li Ziming, Yang Jun, Li Xiangkong, Jiang Yafei, Zhang Kaijian, Wu Jinhua, Wang Guoning, Zhang Dongmei, Wang Xingyi, Meng Chengsheng, Li Yanbin, Zhang Zixu, Chen Weiyi, Jiao Mengjia, Jia Hao, Li Jing, Zuo Haonan, Wang Yan, Gu Man, Xie Meixia, Wu Lizhu, Li Zhikun, Yan Yuanyuan, Cui Yanru, Liu Jie, Wang Xingfen, Ma Zhiying
Abstract excerpt
Limited pangenome and ambiguous genomic architecture constrain comprehensive genetic variation discovery and cotton improvement. Here we assembled a telomere-to-telomere (T2T) genome for elite cultivar NDM13 and near-T2T genomes for 27 additional representatives of Gossypium hirsutum over the recent century, with transcriptomic profiling of 15 distinct tissues from each. We uncovered 51,551 one-to-one conserved...
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